vaccines

Episode 27 - Macaque Prison Gangs

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In this episode, we're talking cure for the common cold... or at least, a vaccine for it. Also, Kevin and Matt read the wrong paper, Chadene corrects Kevin's pronunciation of her name (again!) and we give a big round of applause for Dr. Kate Franz (though she's still too busy for us).

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Links

The Paper: A polyvalent inactivated rhinovirus vaccine is broadly immunogenic in rhesus macaques
Guardian article about the effort to develop a rhinovirus vaccine
Chadene's Blog - The SciMinded Idealist (and her post about episode 26)
Kevin's Beer - Left Hand Milk Stout

Episode 25 - You're famous if you have a wikipedia page

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OMG, Audiommunity is back! With a... vengeance? That doesn't make any sense. But we're back!

We've got a couple of new hosts - Please give a warm welcome to Chadene Tremaglio and Camilla Engblom! Kate is still holed up in a cave (lab) trying to wrap up her PhD. But she'll soon return... we hope...

Audiommunity is now accepting donations via Patreon. The way it works is that you set up a pledge amount that we'll get each time we release an episode (up to a maximum you set). We'll keep doing this for free, but if you value the podcast, please consider tossing a buck or two our way!

Links

The "original" alcoholic ginger beer
Thomas Benjamin (Chadene lied... there's no wikipedia page!)
Filtered Fecal Transplant Paper
Evo Devo (Desposito Cover) - Also check out this guy's patreon page, this stuff is great!
 

Episode 3 - Immunologists' Dirty Little Secret

Click here to download episode. Fungal hyphae growing on Toll mutant D. melanogaster

Today, we're talking the other immunity (that both Kate and Kevin happen to study). Neglected for nearly one hundred years, the innate immune system is required for getting inflammation going, and without it, adaptive immunity wouldn't function.

We discuss a landmark paper by the late Charles Janeway that set the stage for the revolution in understanding, and a newer study that aims to use our modern understanding of the innate immune system to make better vaccines. Check back later for some graphics and explainers.

CORRECTION: "Variola" causes smallpox, not chickenpox. The chickenpox virus is "Varicella." Thanks to listener Robin Datta for the correction.

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Links:

Approaching the Asymptote: Evolution and Revolution in Immunology

Programing the Magnitude and Persistence of Antibody Responses with Innate Immunity

Blog post Kevin wrote about the Nobel Prize in physiology or medicine - it's a bit controversial (make sure to read the comments too!)

More controversy about the history on the fly side from Bruno Lemaitre (who did the work in Jules Hoffman's lab on fly Toll and immunity)