Episode 21 - Allergies Suck Less than Cancer

Kiwi's are delicious, but sacrificing their consumption to treat your cancer is probably a worthy trade-off. Image from Flickr user eldholm. Click for source

Kiwi's are delicious, but sacrificing their consumption to treat your cancer is probably a worthy trade-off. Image from Flickr user eldholm. Click for source

This week, a guy gets a kiwi allergy from a bone marrow transplant from his sister, Matt envisions a magic mouse, and Kate peaces out after 20 min. Meanwhile, Kevin continues to be the only one drinking... that schtick may not last much longer.


Episode 20 - Bacteriophiles with Jesse Noar

Something a bit different this episiode. Last month, we joined Jesse Noar, host of the excellent Bacteriophiles podcast to record an episode about oncolytic viruses (viruses that blow up cancer cells). We hope you enjoy it, then head on over to microbe world and subscribe to Jesse's podcast. 

Links
Paper: Myxoma virus suppresses proliferation of activated T lymphocytes yet permits oncolytic virus transfer to cancer cells

Episode 19 - J Lo Poop Pills

By SuSanA Secretariat - https://www.flickr.com/photos/gtzecosan/16424898321/, CC BY 2.0

By SuSanA Secretariat - https://www.flickr.com/photos/gtzecosan/16424898321/, CC BY 2.0

In this episode, how parasitic worms alter in immunomodulatory effects of the gut microbiome. Also, Kate expresses her distaste for large datasets and animal experiments, and Matt proposes a weight loss company that will only market to identical twins.

Links

The paper: The Intestinal Microbiota Contributes to the Ability of Helminths to Modulate Allergic Inflammation

Original paper on gut microbes and short chain fatty acids

The company that Kevin couldn't remember: Seres Therapeutics

Episode 18 - More cow... sirens?

Chemical structure of cGAMP - the "A" is on the bottom left, the "G" on the upper right and the "cyclic" part is that linkage in the middle between the sugars and the phosphate groups.

Chemical structure of cGAMP - the "A" is on the bottom left, the "G" on the upper right and the "cyclic" part is that linkage in the middle between the sugars and the phosphate groups.

In this episode, we talk about the innate immune system's Trojan cow strategy - using a cyclic dinucleotide as a signaling molecule means that viruses can package the seeds of their own destruction. 

Meanwhile, Matt and Kate throw Kevin under the bus with regards to alcohol consumption, and Matt expounds on the security threat posed by infectious cattle. 


Episode 17 - When your immune system is all up in it

In this episode we talk about lymphatics in the brain and why that's both obvious and not obvious. Meanwhile, Kate drinks disgusting smoothies and Kevin triggers Matt with a trigger warning.

Gross Smoothie Recipe

2 cups plain kefir
2 Tbsp almond butter
1 cup chopped baby kale
1 banana (Cavendish!)
1/3 cup oatmeal
1/2 scoop protein powder
1 dash cayenne pepper

Blend all ingredients, hold nose and consume. 
 

Links:

The Paper: Structural and functional features of central nervous system lymphatic vessels
The Structure of Scientific Revolutions
Lymphatic System